The association finasteride & blend-containing growth factors by bacterial reverse mutation assay
The psychologically impactful hair loss caused by a hereditary pattern, known as androgenetic alopecia (AGA), can occur in men as in women. Among medicines, finasteride has been used in association with blend-containing growth factors. The objective of this work was to evaluate the effects of the association between finasteride & blend-containing growth factors using a bacterial reverse mutation assay. Both compounds or in the mixture were subjected to TA97a, TA98, TA100, and TA102 with (+S9) and without (-S9) metabolic activation, using different concentration and combinations.