Antitumoral activity and in vivo toxicity of cnidoscolus quercifolius pohl (euphorbiaceae)
Ethnopharmacological relevance Cnidosculos quercifolius Pohl, commonly known as faveleira, is a plant widely used as a folk medicine used as phytotherapy. From the plant roots of this genus, some activity is reported in the literature as antioxidant potential, inhibition of cellular carcinogenic and antimicrobial agents, among others. Purpose: This work was designed to investigate the faveline rich fraction (FRF) obtained from the root bark for their acute toxicity when administered orally, in vivo antitumor activity evaluated in mice inoculated with sarcoma 180 tumor cells.