Life Sciences

Antitumoral activity and in vivo toxicity of cnidoscolus quercifolius pohl (euphorbiaceae)

Ethnopharmacological relevance Cnidosculos quercifolius Pohl, commonly known as faveleira, is a plant widely used as a folk medicine used as phytotherapy. From the plant roots of this genus, some activity is reported in the literature as antioxidant potential, inhibition of cellular carcinogenic and antimicrobial agents, among others. Purpose: This work was designed to investigate the faveline rich fraction (FRF) obtained from the root bark for their acute toxicity when administered orally, in vivo antitumor activity evaluated in mice inoculated with sarcoma 180 tumor cells.

Agribusiness in the Brazilian Amazonia: A general overview

This work presents a study on agribusiness in the Brazilian Amazonia (Legal Amazonia) to characterize the use of land, production, and export agricultural and livestock of the member states. The results show that agribusiness applied sustainably reduces negative environmental impacts. However, the population's salary is still lower compared to the rest of Brazil. Finally, this work presents a proposal to create an Amazonian Observatory of Agronomic Knowledge (OBAMA) to promote social, economic, and environmental sustainability in the Legal Amazonia.

The general data protection law in health

This article addresses the General Data Protection Law (LGPD) and its applicability in health, to ensure the security and privacy of the patient's personal data, generated in the health unit. Objective: to seek to identify the security mechanism adopted by the health organization for the storage and treatment of patient data, informed during the provision of medical and hospital services.

A criança e a morte: um estudo acerca do lúdico no processo de luto infantil

O luto infantil é cercado de senso comum, no qual de maneira errônea a criança é vista como a incapaz de compreender ou lidar com a morte. Ao contrário do que se tende a pensar, a criança consegue sim assimilar a perda e se sensibiliza com esta realidade. Nessa perspectiva, a criança possui a capacidade compreensiva a respeito da vida e da morte, e pode expressar seus sentimentos através do lúdico.

Investigative activities in science teaching: the use of problem-based learning with high school students

This work aims to present the results of a chemistry class held with students from the three high school grades. The learning of chemistry concepts was evaluated based on the contribution of experimental class in the process of understanding the chemical phenomena studied. The results demonstrated that Chemistry can be better understood if viewed as a visual science, but the interconnection between macroscope, microscope and symbolic levels needs to be sought to provide better understanding and positively influenced to student formation.

Terapia nutricional enteral domiciliar: uma revisão integrativa

Este estudo teve como objetivo analisar as evidências científicas disponíveis acerca da Terapia Nutricional Enteral Domiciliar (TNED), analisando as condições de manejo desta terapia e possibilidade de desenvolvimento de ações, principalmente no âmbito da Estratégia Saúde da Família (ESF). Trata-se de uma revisão integrativa da literatura, com vistas a responder a seguinte questão: “Quais as principais evidências científicas disponíveis sobre TNED relevantes para um manejo adequado desta terapia?”. 10 estudos foram elegíveis de acordo com os critérios estabelecidos.

Consumption of alcohol by blind people

The study aims to analyze the pattern of alcohol consumption by blind people. Cross-sectional study, with 31 blind people registered in Family Health Units. A identification questionnaire and the AUDIT test were used to collect data. Data were analyzed using the statistical software. The average age was 66.48 years, 67.7% were male, 38.7% were married, 41.9% were illiterate, 93.5% had no employment, 90.6% had family income between 1 and 3 minimum wages, 64.5% were Catholic, and 58.1% lived with siblings, grandchildren and nephews. Over 50% of participants had acquired the blindness.

Preventive use of resveratrol increases its antioxidant capacity in neuro-2a cells

Cerebral aging is a phenomenon determined almost exclusively by oxidative stress, accumulation of macromolecules damaged by oxidation and changes in the structure and function of neurons, being a risk factor for several diseases. Many data support the important role of oxidative stress in the aging process and neurodegenerative diseases, suggesting the beneficial effect of antioxidants as an adjuvant therapy.