Placental hla-g expression among women living or not with HIV-1
Introduction: The immune checkpoint HLA-G molecule is highly expressed in the placenta’s extravillous trophoblast cells and has a pivotal role in immune tolerance during pregnancy. Since HIV-1 can infect trophoblast cells and may modify HLA-G expression to subvert host immune defenses, in this study we evaluated the HLA-G expression in third-trimester placental tissue of women living or not with HIV-1.