Life Sciences

Duchenne Muscular Dystrophy (DMD) is considered to be the most common muscular dystrophy. It is caused by changes in the DMD gene that is responsible for the production of the protein dystrophin. It predominantly affects the male sex, with an incidence of one in three thousand five hundred (1: 3,500) live births, the female sex is usually asymptomatic carrier. The first symptoms of DMD are characterized by balance deficits, frequent falls and difficulty lifting and jumping due to weakness in the muscles that initially affect the lower limbs.

This work evaluated the antiadhesive activity of two microbial exometabolites: indole and pyocyanin. The in vitro quantitative microtiter adherence assay was carried out with Pseudomonas aeruginosa exposed to concentrations of 0.5 and 1.0 mM of indole and Escherichia coli exposed to 0.2 mM of pyocyanin. The incubation took place for 48 hours at 30ºC. Afterwards, the violet crystal test was performed and optical density measurements (590 nm) were used to calculate the percentage of adhesion relative to the control tube, in which the cells were cultured in the absence of exometabolites.

The present investigation is aimed at assessing the current Ground Water Quality standard of Jammu City in terms of Physico-chemical parameters. In the selected study area the talab tillo is receiving considerable amount of man made products such as gasoline oil , road salts, and chemicals get into the ground water and witnessing an untreated waste from septic tanks and toxic chemicals from underground storage tanks and leaky landfills to contaminate the ground water.

The objective of this research was to compare the physical-chemical, spectroscopic and fatty acid profiles of Brazil nut oils from the 2018 and 2019 harvests. The methodological procedures followed the internationally accepted standards of the American Oil Chemist’s Society. The analysis of the physical-chemical properties showed oils with high quality for human consumption, within the quality standards defined by Brazilian legislation. In relation to the different harvests, during the analyzed period, they did not present differences maintaining their high quality as a function of time.

This study aims at evaluating the prescription of serum protein electrophoresis and at analysing the different electrophoretic profiles found in current practice at the biochemistry laboratory of the University Hospital Center of Joseph Ravoahangy Andrianavalona. This is a descriptive retrospective study over a period of 8 months from November 1, 2018 to June 30, 2019. All patients with serum protein electrophoresis prescription were included. In total, 77 serum protein electrophoresis were collected with 38 female and 39 male sera.

Lignin contained in the black liquor generated during alkaline delignification of cellulose for bioethanol production was precipitated with H2SO4 and evaluated as biosorbent of Pb(II) ions in aqueous solution. Experimental design (DOE) and response surface methodology (RSM) were carried out in order to reduce the number of experiments and achieve the best conditions for biosorption procedure. Three factors at three levels were studied: initial pH (3; 4 and 5), biosorbent mass (50 mg; 100 mg and 150 mg), and initial Pb(II) concentration (40 mg L-1; 60 mg L-1 and 80 mg L-1).

No presente texto serão apresentadas reflexões sobre a Alfabetização Científica e Tecnológica e sua relação com a formação do cidadão. Problematizaremos o papel da escola e sua importância para a alfabetização científica dos estudantes. Serão discutidos os conceitos de alfabetização científica, letramento e enculturação científica, como estes se integram e se complementam.

Characterization of gum Arabic is of paramount importance especially when it is intended to be used as a natural additive in a wide spectrum of pharmaceutical and food industries. In this study, laboratory procedures as well as biochemical tests were used to investigate the effect of some bacteria species on the characteristics of Acacia Senegal var. Senegal gum Arabic stored for different periods. The results revealed that dried gum Arabic, kept under long-term storage, is more resistant to biodegradation than the freshly harvested one.

Grewiatenax fruits as nutritional supplement are being widely used in traditional medicine in most parts of Sudan to treat anemic patients. This study was conducted to specify the most productive method for extractingG. tenax fruits and to standardize and formulate the extract into effervescent tablets. The fruits were extracted by hot and cold extraction with maceration using 80%, 65%, and 50% ethanol strength and the extracts were standardized. Two formulae (F1 and F2) were prepared from the extract and compressed into tablets.

The discovery of new molecules with antimicrobial activity and the understanding of the mechanisms of action involved are important strategies against multiresistant pathogens.Given this perspective, the positive α-pinene enantiomer appears as an alternative to combat them, as it inhibited the growth of microorganisms, including strains of Staphylococcus aureus, which gives it the possibility of its use as an isolated antimicrobial agent or in combination with other drugs.The aim of this study is to evaluate the sensitivity profile of S.