Prescription of serum protein electrophoresis: on 77 tests carried out at hjra biochemistry

This study aims at evaluating the prescription of serum protein electrophoresis and at analysing the different electrophoretic profiles found in current practice at the biochemistry laboratory of the University Hospital Center of Joseph Ravoahangy Andrianavalona. This is a descriptive retrospective study over a period of 8 months from November 1, 2018 to June 30, 2019. All patients with serum protein electrophoresis prescription were included. In total, 77 serum protein electrophoresis were collected with 38 female and 39 male sera. The patients’ age was from 1 to 82 years with an average age of 49 years and a sex ratio of 1.02. Out of the samples that were analyzed, 12.98% of the profiles were qualitatively and quantitatively normal. Monoclonal spikes were found in 9.1% of the cases. The departments which request it were external service (35.06%), rheumatology dermatology (14.30%) and oncology departments (6.49%). Electrophoresis gives a panoramic view of the whole serum proteins and can detect various pathologies. For a correct interpretation, the collaboration between clinician and biologist is always important.