Successful integration of transplanted mesenchymal stem cells into the livers of Schistosoma mansoni-infected mice
One of the most serious consequences of Schistosoma (S.) mansoni infection is hepatic schistosomiasis or periportal fibrosis. Treatment with praziquantel (PZQ) remains the mainstay of schistosomiasis control. Stem cells and their possible use in cell therapy have drawn much attention recently, due to their potential for self-renewal and differentiation. The present study aimed to investigate the ability of umbilical cord-derived mesenchymal stem cells (UMSCs) to integrate into the livers of S. mansoni-infected mice. S.