Life Sciences

Avaliação farmacocinética e farmacologia in silico de 3-seleno flavonoides idealizados

O câncer de mama é o que mais acomete mulheres em todo o mundo e com resultados clínicos satisfatórios em apenas 30-40% dos casos, há urgência por novos alvos moleculares e terapias. Os estrógenos, ligantes naturais dos receptores de estrogênio alfa e beta (REα e REβ), ao se ligarem ao REα podem desencadear este tipo de câncer. Ao contrário do REα, o REβ demonstrou ser capaz de reduzir a proliferação celular e conduzir a apoptose, principalmente quando ligado a moduladores seletivos, como o fitoestrógeno daidzeína.

Growth of the mangrove oyster crassostreagasar (deshayes, 1830) reared with suspension techniques on the coastal lagoon in benin, west africa

The exploitation of the mangrove oyster Crassostreagasar is an income-generating activity for the riparian populations of the lagoons of southern Benin. The traditional bottom farming is the most widespread oyster farming method along the coastal lagoon. This study aims to cultivate the oyster with suspension techniques in order to increase oyster production. Rearing trials were carried out between September and October 2017 with vertical suspension technique, horizontal suspension technique and the floating line in different stations.

Estratégias didáticas para a aprendizagem da leitura e escrita nos anos iniciais do ensino fundamental: uma revisão sistemática

Objective: To carry out an systematic literature review to understand the methodological strategies for didactic interventions that facilitate the child's entry into reading and writing learning in the early years of elementary school. Materials and Methods: It was carried out a literature survey in the CAPES Periodicals and Google Academic databases in August 2021. Thus, it was selected 09 papers and included according to the eligibility criteria.

Evaluation of female gender violence prevalence during the pandemic: an Integrative review

The COVID-19 pandemic started in 2019 and caused various modifications in our social structure. Social isolation at home during the pandemic was an obligation that posed challenges, especially for women who often needed to live with their abusers. This review has the objective of profiling women abused within their household during the pandemic. Method: This study represents a qualitative approach, in the format of an integrative review of literature.

Consumo de alimentos ultraprocessados e o diabetes mellitus: relações com a saúde e com o meio ambiente

O Diabetes Mellitus (DM) é uma doença crônica e quando mal controlado pode levar a complicações clínicas devastadoras. A alimentação é parte fundamental para a prevenção e controle não farmacológico do DM, e por isso, as mudanças nos padrões alimentares ocorridas nos últimos anos, incluindo o maior consumo de alimentos ultraprocessados, tem sido de grande relevância no contexto do DM. Não pode deixar de ser considerado são as repercussões para o meio ambiente do aumento da produção de alimentos ultraprocessados.

Práticas pedagógicas dos professores da educação básica para atrair a atenção dos alunos que têm aulas remotas no período de pandemia do covid-19: uma revisão sistemática

Introduction: Over the COVID-19 pandemic period, it was necessary the adaptation to the emergency pedagogical practices to meet the needs of the educational system and minimize school closures and digital teaching practices have been part of the solution, offering distance learning. Objectives: Carrying out a literature review on pedagogical practices of basic education teachers who have the attention of remote students in the period of the COVID-19 pandemic.

Composition chimique des huiles essentielles des plantes aromatiques utilisees dans la lutte contre les bruches de haricots en republique du congo

Au Congo, avec des pertes des grainesen stockage qui avoisinent 60 %, la lutte contre les bruches est devenue une priorité. La méthode traditionnelle préconisée est l’utilisation des feuilles ou derhizomes deLippia multiflora, Cymbopogon citratus, Chenopodium ambrosioides, Ocimum gratissimumetZingiber officinale. Cette étude vise à déterminerles composés chimiques des huiles essentielles des cinq plantes aromatiques utilisées par les producteurs pour lutter contre les bruches haricots et de pois cajan.

Associação da complexidade do cuidado de enfermagem e perfil de pacientes clínicos internados em uso de sonda nasoenteral, segundo o sistema de classificação de pacientes proposto por fugulin

Objective: to analyze the association of the complexity of nursing care using the Fugulin Scale and the profile of hospitalized clinical patients using a nasoenteral probe (SNE). Method: Cross-sectional, retrospective, quantitative study, using secondary data, from a multicenter study.The sample comprised 31 patients admitted to the medical clinic of a hospital in the countryside of Rio Grande do Sul, using SNE. Results: most male patients, white, educated, married, aged over 60 years, requiring high dependency care, according to the Patient Classification System proposed by Fugulin.

Identification of protozoa and helminths in feces samples of capybara (hydrochoerus hydrochaeris) that inhabit the lagoa maior in tres Lagoas, Brazil

The capybara (Hydrochoerus hydrochaeris) a semi-aquatic generalist herbivores found in South American. The objective was to evaluate the presence of parasites in wild capybara species that inhabit the Lagoa Maior region in Tres Lagoas Brazil. Four stool samples were collected totaling 20 samples per collection (2 in dry periods and 2 in rainy periods). Stool samples were processed using standardized parasitological techniques and the observation and identification of the parasitic forms was carried out through optical microscopy and morphological and morphometric evaluation.

Isolation and structural elucidation of secondary metabolites from allophylus semidentatus of the extracts and their antimicrobial, antioxidant and cytotoxic activity

Some Sapindaceae plants are used in folk medicine, food and also in the pharmaceutical field. Allophylus semidentatus (Sapindaceae) is a wild plant that is being studied for the first time. In this investigation, the metabolites were extracted by using polar solvent as methanol, hexane, chloroform and ethyl acetate. Chromatographic and spectroscopic techniques were used for the isolation and identification of compounds. Extracts from the branches revealed the presence of steroids/triterpenes, flavonoids, alkaloids and coumarins. Metabolites were isolated by chromatography.