Biochemical and histological parameters in induced type 2 diabetic rats fed with high fat diet without exogenous cholesterol and low-dose streptozotocin
The objective of the present study is to establish a rat model for diabetic type 2 (T2DM) fed with high fat diet without addition of exogenous cholesterol and low streptozotocin (STZ) dose aiming higher survival rate under the local experimental conditions for evaluating sources of biodiversity to supply alternative energy for T2DM individuals mainly from the Pantanal (wet land) and the Savanna-like area (Cerrado) of the Mato Grosso do Sul State.