Past Issue

Use of Cannabinoids in Alzheimer's Disease: integrative Synthesis of the Literature

Introduction: Alzheimer's disease (AD) is an incurable neurodegenerative condition with limited therapeutic options. Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC), derived from Cannabis sativa, show therapeutic potential due to their neuroprotective properties and interaction with the endocannabinoid system (ECS). Objectives: Synthesize and evaluate the available scientific evidence on the use of cannabinoids in the treatment of AD.

Prediction of Physicochemical, Pharmacokinetic and Toxicological Parameters of Antimicrobials in Phase III Clinical Studies

In silico analysis importance was recognized. It provides a predictive evaluation of the molecular behavior, revealing physicochemical properties and pharmacokinetic and toxicological informations that determine how much promising is a molecule to advance to other pharmaceutical tests. Therefore, this work aimed to present the traditional antimicrobials in phase III clinical studies, attaching, through in silico analysis, their pharmacokinetics, adverse effects and toxicity to their molecular structure and physicochemical properties.

Prevalence of Patellofemoral Pain Syndrome in Patients with Anterior Knee Pain in South Gujarat

Introduction: Abstract- Patellofemoral pain (PFP) is recognized as one of the most common lower-extremity disorders encountered by orthopedic physical therapists. PFPS is defined as pain around (peripatellar) or behind the kneecap (retro patellar) that is aggravated by activities loading the knee joint, such as running, squatting, climbing stairs or even prolonged sitting with knee flexion above 90 degree. It is one of the most common knee conditions clinicians encounter in young and active individuals.

How to Train Teachers Prepared to use Digital Technologies that Influence the Social Movements of Children at School: A Systematic Review

Introduction: Teacher training is a central element in the development of quality education. This training involves not only the acquisition of pedagogical knowledge, but also the development of skills that allow educators to adapt to new demands and challenges. The general objective of the study was to critically analyze teacher training for the use of digital technologies that influence children's social movements at school.

Introduction to Industrial Fatigue

Fatigue results in slower reactions, reduced ability to process information, memory lapses, absent-mindedness, decreased awareness, lack of attention, underestimation of risk, reduced coordination etc. Fatigue can lead to errors and accidents, ill-health and injury, and reduced productivity. Fatigue dramatically increases the risk of accidents and injuries in the workplace, and reduces productivity and performance. Prolonged fatigue can cause serious physical and mental health problems. Fatigue is a lack of energy and motivation.

Survey of the Knowledge of Elderly People Regarding Non-Conventional Food Plant

The acronym PANC refers to all plants that have one or more edible parts, whether they are spontaneous or cultivated, native or exotic, and are not included in our daily diet. Non-Conventional Edible Plants (PANC) are vegetables that have been known and used for many years in indigenous culture, but which have ceased to be prominent today, being underutilized by the population. Brazil currently has one of the greatest biodiversity in the world, however, the plant species used in food are still scarce.

Assessment of medication discontinuation in hypertensive and diabetic patients after bariatric and metabolic surgery

Introduction: Epidemiological studies show a significant acceleration in the prevalence of obesity in Brazil and worldwide, making it a public health issue, primarily due to the increased risk of diseases such as systemic arterial hypertension (SAH) and type 2 diabetes mellitus (T2DM). The first-line treatment for obesity is lifestyle modifications and pharmacological measures.

How long do directors stay on the board to contribute positively towards the financial performance of plcs in Malaysia?

This study investigates the relationship between the length of time board members serve and the financial performance (FP) of Malaysia's top 500 public listed companies (PLCs). The research uses data from annual reports, secretarial data, and financial statements to analyse the correlation between board tenure (BTEN) and FP. The study found a mean of 8.18 years in BTEN but found no impact on FP. The findings will enhance understanding of corporate governance (CG) and FP in Malaysia, particularly within the Malaysian Code on Corporate Governance (MCCG) framework.

Comparative study of evaluation of sensory processing disorder with the Atlas.Ti

Sensory Processing Disorder (SPD) is reflected in unexpected actions and inappropriate behavior for no apparent reason. It is a complex condition that involves the central nervous system and is not evident in clinical examinations. Introduction: Identifying the patient's reactions to everyday situations helps health professionals to recognize sensory integration difficulties and establish a treatment plan, which begins with assessment. Objective: To identify the assessment most commonly adopted by SPT researchers.