Life Sciences

An integrative review of genetic testing for the diagnosis of autism spectrum disorder

The purpose of the study is to verify in the literature in a systematized way studies that prove the efficacy of genetic tests in the diagnosis of Autism Spectrum Disorder. Data were collected from the Research Databases of the Virtual Health Library and PubMed, using the combination of the following keywords: Genetic tests AND autistic spectrum disorder diagnosis. Articles from 1980 to 2020 were researched in the Portuguese, English and Spanish languages of national and international journals and included 17 full-text articles, in English, from PubMed to make up this study.

Alcachofra (Cynarascolumus L.) melhora o metabolismo oxidativo em ratos diabéticos

O diabetes mellitus é considerada uma doença crônica e está entre as emergenciais. A alcachofra vem sendo relatada com potencial atividades antibacteriana, anti-inflamatória, antioxidante e hipolipidêmica. O presente trabalho avaliou os efeitos do extrato da alcachofra na prevenção das complicações crônicas do diabetes mellitus. A droga vegetal foi adquirida comercialmente. O extrato seco foi obtido por maceração hidroetanólica (70% v/v). Utilizou ratos da linhagem Wistar machos, estes foram submetidos ao Aloxano (150mg/kg, em salina 0,9%) intraperitoneal.

Urban mobility in smart cities: a case study in the city of curitiba

This study addresses the urban mobility in the city of Curitiba, whoseissue is of vital importance for large cities, directly impacting the quality of life of citizens. Curitiba has been recognized worldwide for the quality of its public transportation, especially with the introduction of the Bus Rapid Transit and its exclusive lanes, but in recent years the city has suffered a negative impact due to the growth of the automobile fleet and the lack of investment in public transportation in new modes to meet the needs of users.

Supplementation in vegetarian pregnant: nutrients and vitamins that require more attention

This article is a review of the nutritional aspects of vegetarian diets (including vegan) during pregnancy, pointing out the aspects that require more attention and where there is a risk of deficiency. This article contains recommendations made from the current literature. The bibliographical survey was carried out on the bases PubMed, Scopus, Web of Science and Embase, Cochrane, Ovid, Periodicos.com, Harvard Library, and Google Scholar.

Profile of drugs used in patients with covid-19 in two hospitals in santa catarina

Introduction: the first reports of the disease caused by SARS-Cov-2 emerged in Wuhan, China in late 2019, and the causative agent and its ability to cause pneumonia, respiratory failure, and eventually death were soon identified more clearly. Based on the accurate study of the disease, several studies have emerged in an attempt to find a treatment, and there are currently more than 4,000 clinical studies related to the subject. Objectives: to perform a data research regarding the main drugs used in patients with COVID-19 in two hospitals in Santa Catarina, using these data to improve care.

Análise espacial e epidemiológica dos casos notificados de leishmaniose visceral humana em área endêmica, no estado do Maranhão, Brasil

Introdução: A Leishmaniose Visceral (LV) é uma doença endêmica no Brasil, no entanto têm sido registrados surtos frequentes, sendo estimada que cause a nona maior carga de doenças entre as patologias infecciosas individuais. Objetivo: analisar os dados clínicos- epidemiológicos e a distribuição espaço-temporal dos casos notificados de LV humana, no município de CaxiasMaranhão. Métodos: trata-se de um estudo de caráterdescritivo-exploratório com abordagem quantitativa, de recorte transversal no período de 2014 a 2019, realizada em Caxias, Maranhão localizada na Região Nordeste do Brasil.

A conceptual model for artificial moral agents (ama) in the educational context

As the area of artificial intelligence (AI) evolves and reaches new spaces, showing itself capable of promoting real changes in the way people interact, solve problems and make decisions, it becomes more urgent to make it predictable, responsible, and reliable. Thus, solutions for the values alignment (VA) in AI have been proposed in recent years. The present study proposes a model of artificial moral pedagogical agents (AMPA), adopting a top-down approach and the classic BDI model. In this article, we describe why the top-down approach is the best approach to educational grounds.

Color perception in children with sicklecell anemia and potential impacts in cognitive development

The sicklecell anemia is acknowledged as a global public health issue by the World Health Organization, associated to physiological and cognitive changes. In Brazil, there is a lack of neurocognitive research in sick children. This research assessed color vision in 20/20 acuity and with no peripheral retina lesions with normal controls. Saturated and desaturatedLanthony tests D15 were used to compare both groups. 134 children participated of this study within 6-11-year old age range.

A study in the field of probability: a bibliometric application

Although the search information is the foundation of knowledge, a large amount of information without treatment and classification can make it harder to find instead of easier. Several tools are used to prevent this problem. This paper uses a bibliometric approach to the analysis of books published in the last few decades related to the subject of probability, applied probability and probability problems. First, we present historical aspects and rules of a bibliometrics, then a practical application.

The educator and the educational practices in hospital spaces: conceptual and contextual epistemologies

This article aims to demonstrate the importance of hospital pedagogy as a field of knowledge and the need of the professional of this field, the hospital pedagogue, to act in the scope of the multiprofessional health team, not only as a doctor, psychologist or nurse, but as an educator/teacher who makes the teaching-learning process possible in peculiar circumstances in which the ill schoolchild is inserted. Methodologically, this is a theoretical-epistemological study, of exploratory-descriptive type as to the content of the sources.