Clinical reports of 31 brazilian case presentations with fibrodysplasia ossificans progressiva
Fibrodysplasia Ossificans Progressiva (FOP) is a rare autosomal dominant disease, caused by heterozygous mutation in the type I activin receptor gene on chromosome 2q24 that, due to instability, causes progressive ectopic ossification. The objective of the present study was to evaluate the characteristics of 31 patients with FOP from different regions of Brazil. Some characteristics include current age, flare ups, disease progression, hallux characteristics, diagnosis, ectopic ossification sites, and symptoms of cramps, temporomandibular joint, dental conditions and previous surgeries.