Incidência de defeitos de fechamento de tubo neural no Brasil
Objective: to analyze the incidence of neural tube closure defects by Brazilian states and regions before and after the mandatory supplementation of folic acid to flour. Methods: public data available for access in the DATASUS SINASC database were used, corresponding to the period between 1999 and 2016, and 2002 was the start date of supplementation, in relation to the incidence of spina bifida in live births in the national territory.