Wolbachia method as a Dengue control Strategy in Brazil

Dengue represents a significant public health challenge in Brazil, with thousands of cases reported annually. Effective control of this disease requires innovative and sustainable approaches. In this context, the Wolbachia method emerges as a promising strategy, harnessing the ability of this endosymbiotic bacterium to reduce the vector competence of the Aedes aegypti mosquito, the dengue virus transmitter. This integrative review assessed its effectiveness in Brazil, using scientific articles from PubMed, SciELO, and BVS databases from 2019 to 2024. Selected studies with the keywords "Brazil", "Dengue Virus", and "Wolbachia Method" demonstrated a significant reduction in disease incidence following its implementation in affected areas. Complementarity with socio-environmental measures, such as waste management, is essential to sustain these results. Despite its promise, technical challenges and the need for research investment to expand its implementation against additional arboviruses are crucial for its continued effectiveness.