Synthesis and characterization of new schiff-bases derived from 3-nitrophthalic anhydride via its hydrazide derivative
International Journal of Development Research
Synthesis and characterization of new schiff-bases derived from 3-nitrophthalic anhydride via its hydrazide derivative
Received 24th February, 2017; Received in revised form 27th March, 2017; Accepted 09th April, 2017; Published online 18th May, 2017
Copyright©2017, Jinan. M. abdulrasool and Emad. T. Ali. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
New N-(4-hydroxy phenyl) 3-nitro phthalimide (II) was synthesized from its amic acid (I) using soduim acetate – actic anhydride system as dehydrating agent, which was trarsfered to new ester(III) by the reaction with chloro ethyl acetate, (III) was used to prepare the new hydrazide derivative (IV), this hydrazide was allowed to react with different aldehydes to give their new Schiff-Base derivatives(the hydrazone) (V-IX). All the new compounds were characterized by their m.p., FTIR, C,H,N analysis and 1HNMR for some of them. Schem (1) shows the reaction steps used to prepare the proposed Schiff-Bases.
