Study of Urinary Hydroxyproline, Serum Pseudo Choline Esterase, Serum Protein Electrophoresis Abnormalities in Pem Children

Introduction: Hydroxyproline is a translation modification of amino acid for the formation of collagen in PEM (Protein energy malnutrition) children the hydroxylproline is excreted through urine not seen.The pseudo choline esterase lowers in the PEM children because of liner enlarged and impaired LFT and at the same time, the hypoalbuminemia is observed by an electrophoretic pattern of A: G ratio. Materials and Methods: This case-control study was carried out in the Index Medical College, Department of Pediatrics. This study population consisted of 75 cases of PEM and 50 controls. The data and complete clinical history of the subjects wascollected in association with the departments of Social and Preventive medicine and Pediatrics. The analysis of urinary hydroxyproline, serum pseudo choline esterase and A: G ratio of proteins by electrophoretic pattern was done. Results: In PEM childrenthe analyzed parameters are significantly lowered compared tonormal healthy children these parameters observed from PEM children are useful for the control of the mortality and morbidity rate in children. Conclusion: This study mostly says that nutritional dwarfing of protein deficiency calories is seen in this condition. The clinical finding of electrophoretic pattern protein separation is very low bands appear the band are densitized by densitometry.