Production of biomolecules of pharmacological interest by trichoderma species
International Journal of Development Research
Production of biomolecules of pharmacological interest by trichoderma species
Received 10th November, 2021; Received in revised form 14th December, 2021; Accepted 06th January, 2022; Published online 20th February, 2022
Copyright © 2022, Wesley Cristian Ferreira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The genus Trichoderma comprises more than 400 species of fungi distributed across all ecosystems worldwide. Fungi of this genus have been widely reported to produce metabolites with various activities, which have been used in diverse areas such as in pest biocontrol, resistance induction in plants, and production of biomolecules of biotechnological interest. This review aims to provide an overview of the main species of Trichoderma that produce biomolecules with activities that are useful in the biotechnological field, emphasizing metabolites with antibacterial and antitumor activity. We have provided an overview of 21 different species of Trichoderma and 59 metabolites that display activity of interest. In addition, more than 500 other metabolites have been reported in the scientific literature, which have not yet been tested or have not been demonstrated to show activity of interest with respect to the scope of this review, providing ample possibility for many other biotechnological applications of Trichoderma biomolecules.
