Primary hyperparathyroidism: Single center experience

Primary hyperparathyroidism (PHPT) results from inappropriate overproduction of parathyroid hormone from one or more adenoma, hyperplasia or less commonly carcinoma. The incidance of PHPT in USA is 1/700 and male/female ratio is 1/3 .  PTH is mostly demostrate as adenoma. 80% of the cases present with solitary adenoma. We conducted this study to investigate the 6 patients that were diagnosed and operated for primary hyperparathyroidism between the years 2007-2013. 6 patients who diagnosed and operated for primary hyperparathyroidism in our clinic between 2007-2013 were analysed retrospectively. All of the 6 patient were female. The age avarage was 56 (48-66). The avarage of plasma calcium levels were 12.1 mg/dl (11.5-13.2mg/dl) and plasma parathormone levels were 240 pg/dl (190-550 pg/dl). Preoperative adenoma localisation with neck region USG could only achieved in 3 patients (50%). However the sensitivity of Tc sesta MIBI scintigrapy was 100%. All of the adenomas were located and extracted and there were no mortality or morbidity among the patients. We think taht the macroscopic evaluation of the tumor by an experienced surgeon is more appropriate and the frozen involved pathological examination could be useful for the identification of the sample as a parathyroid gland. We used the USG together with scinthigraphia for the preoperative localisation and direct adenoma excision were made succesfully with unilateral neck exploration in all patients. As a result of minimal invasive surgery no complications occured in our patients.