Pattern of metabolic syndrome among systemic lupus erythematosus patients attending in a tertiary care hospital

Systemic Lupus Erythematosus (SLE) patients having metabolic syndrome (MS) are at increased risk of future cardiovascular disease. This cross-sectional study is done for one year to find out the different patterns of metabolic syndrome among SLE patients, were evaluated according to the case record form with particular reference to patterns of metabolic syndrome. All investigations were done in the Biochemistry Department of CMCH and also in some recognized Private Laboratory if those are not available at CMCH. Among all 40 patients 7(17.5%) patients were having metabolic syndrome, 15 patients (37.5%) were suffering from Hypertension, 9 patients (22.5%) had increased waist circumference, 1 (2.5%) patient had diabetes, 11 (27.5%) patients had low HDL & 16 patients (40%) had raised triglyceride Level. Among the patients with metabolic syndrome, all of them (100%) had hypertension, 3 (42.8%) had increased waist circumference, 1(2.5%) patient had diabetes, 4(57.1%) patients had low HDL and 6(85.7%) patients had high triglyceride level. The study showed that 15(37.5%) patients were hypertensive and one (2.5%) patient was diabetic. All patients were on steroids, half (50%) of the patients were taking Hydroxychloroquine, 11(27.5%) patients were on prednisolone, 11(27.5%) were on both Prednisolone and Hydroxychloroquine, only 1(2.5%) patient was taking MycophenolateMofetil. Ultimately hypertension and high triglyceride were the most common component of Metabolic Syndrome found SLE patients. Chronic Steroid use is a predisposing factor for developing metabolic syndrome.