Experimental model of the murine breast carcinoma (4t1 luc) and evaluation of the effect of acetone cyanidine in the remission of tumor
International Journal of Development Research
Experimental model of the murine breast carcinoma (4t1 luc) and evaluation of the effect of acetone cyanidine in the remission of tumor
Received 22nd January, 2018; Received in revised form 27th February, 2018; Accepted 29th March, 2018; Published online 30th April, 2018
Copyright © 2018, Larissa Schimidt Rosseti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Studies involving the fight against cancer have provided several advances that provide the understanding of the development of tumors, mainly regarding the molecular processes that constitute the structure that allows or enables the progressive transformation of healthy cells into malignant ones.Examinations at the molecular level of tumor development in patients is not very common, since there is a need for biopsies at various stages of transformation. This manuscript is a review that presents and discusses some aspects of the experimental approaches, techniques and strategies used in the study of tumors in murine models with emphasis on the immune response against cancer, specifically the effects of acetone cyanide on tumor remission.
