Clinical Evaluation of Nityavirechana and Trayodashangaguggulu for Managing Katigraha (Low Back Pain) in Overweight and Obese Individuals: An Open-Label Single-Arm Study

Introduction: Low back pain (LBP) refers to discomfort in the lower back. It is a common issue affecting all age groups. There is a correlation between LBP and Katigraha in Ayurvedic texts. According to modern science, LBP is characterized by persistent pain in the lower back. Ayurveda views LBP as a manifestation of doshic imbalance involving Vata, Pitta, and Kapha. Aim of the study: Management of Katigraha with Nityavirechanausing Gandharvahastaditaila, Nirgundikwatha, and Trayodashanagaguggulu. Study Design: Open Label Single Arm Clinical Study Sample Size: 20 Intervention: Nityavirechana for 7 days with Gandharvahastaditaila (10-20ml) as per the koshta and Nirgundikwatha (50ml) early morning on an empty stomach. Shamanaushadi for 15 days from the 1st day of the intervention: Trayodashanaguggulu, two tablets (240mg each) twice daily, morning and night after food with lukewarm water. Study Duration: 15 days. Results: The statistical analysis revealed high significance with p<0.001 for all parameters assessed in the study. Conclusion: The present study provides insight on the use of integrative medicinal formulation in the treatment of lower back pain.