New insights of prolactin in humans: the role of nurses

Prolactin is synthesize by the anterior pituitary gland, by extrapituitary tissues, such as the mammary gland, prostate, skin and brain. It has been relateding to lactogenesis, however, it is known to induce a wide range of functions in different tissues, modulating neurogenesis, neurodevelopment, sleep, learning, memory and homeostasis of the immune system, and may be linked to different types of cancers. The objective was to identify the new insights of the prolactinemia as a biomarker or inducer of pathological processes. During lactation, prolactin promotes milk synthesis and oxytocin stimulates ejection, its increase may come from mechanisms such as nipple sucking stimulus, stress, sexual activity, protein intake, unregulated menstrual cycle and pregnancy, pharmacological or pathological origins. Prostate and breast cancers can be treated using methods to antagonize the PRL receptor and its signaling pathways, which include small molecule-based antagonists of proteins. Drugs to lower the plasma concentration of prolactin are strong candidates to be test in reuse clinical trials to improve the cognitive skills of patients with mood disorder and schizophrenia. Keeping up to date on research, in addition to seeking to evaluate all the variables and biomarkers available for the case, can increase the chance of making an early diagnosis.