Impact of serum sodium on heart rate variability in Dialytic chronic renal patients
International Journal of Development Research
Impact of serum sodium on heart rate variability in Dialytic chronic renal patients
Received 03rd October, 2019; Received in revised form 17th November, 2019; Accepted 04th December, 2019; Published online 29th January, 2020
Copyright © 2020, Viviane Lovatto et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: to analyze the influence of serum sodium (sNa) on heart rate variability (HRV) in chronic dialytic renal patients. Methods: cross-sectional study with comparative approach with subjects undergoing maintenance hemodialysis and a control group. Resting HRV, in time (TD) and frequency domain (FD) analysis, and evaluation of biochemical markers of renal function were performed.The volunteers were allocated into three groups: normotremia dialysis group (NDG), hyponatremia dialysis group (HDG) and a control group (CG). Results: the sample consisted of 32 volunteers, being CG = 10, NDG = 14 and HDG = 8 participants. For the biochemical variables of renal function, there was a difference between CG vs NDG and HDG (p = 0.001). HRV analysis in TD showed that HDG presented a reduction in SDNN (p = 0.002) and rMSSD (p = 0.005) indices compared to CG. For the NN50 index, NDG and HDG presented significant differences in relation to the CG (p = 0.010 and p = 0.001 respectively).While in FD there was a reduction in the high frequency and low frequency band (p = 0.037 and p = 0.007 respectively) in HDG compared to CG. Conclusion: In dialysis patients there is a reduction in HRV, especially in those with hyponatremia.
