Impact of demographic, behavioral, and clinical characteristics on the survival of people living with hiv in the 17th health regional of paraná, Brazil, 2007-2019
International Journal of Development Research
Impact of demographic, behavioral, and clinical characteristics on the survival of people living with hiv in the 17th health regional of paraná, Brazil, 2007-2019
Received 10th January, 2022 Received in revised form 03rd February, 2022 Accepted 11th March, 2022 Published online 22nd April, 2022
Copyright©2022, Rafaela Marioto Montanha et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The aim is to assess survival time and risk of death from AIDS according to demographic, behavioral, and clinical characteristics of people living with HIV. This is a retrospective cohort study. The sample consisted of HIV/AIDS cases in individuals aged ≥13 years notified by the Health Information Systems between 2007 and 2019 and belonging to the 17th Health Regional of the state of Paraná. Survival estimation was performed by using the Kaplan-Meier method and the log-rank test; the multivariate analysis was carried out by using Cox regression. A total of 3,264 records were included. At the end of 140 months of follow-up, 86.9% survived. The individual’s average survival estimation was 120.6 months (95%CI: 118.9-122.3), while for those who died from AIDS-related causes it was 15.6 months (95%CI 13.0-18, 3). The following were associated with shorter post-diagnosis survival time and risk of death from AIDS: age ≥40 years (HR= 1.87; 95%CI 1.51-2.33), lack of education and up to 8 years of schooling (HR= 1.77; 95%CI 1.04-3.05 and HR= 1.63; 95%CI 1.31-2.04), CD4+ T lymphocyte count <350 cells/mm³ (HR=1.32; 95CI % 1.02-1.72) and opportunistic infection (HR= 4.47; 95%CI 3.61-5.33). Disparities in survival among people living with HIV are recognized.
