Human parvovirus in dengue virus negative patient samples in santarém, west region of pará state
International Journal of Development Research
Human parvovirus in dengue virus negative patient samples in santarém, west region of pará state
Received 10th September, 2021; Received in revised form 21st October, 2021; Accepted 29th November, 2021; Published online 30th December, 2021
Copyright © 2021, Cassiano Junior Saatkamp et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The human parvovirus B19 (B19V) is an infectious viral agent associated with mild clinical conditions, such as the benign self-limiting exanthematous disease, but possibly fatal for fetuses. In this study, we observed positive cases of B19V in samples investigated due to suspicious dengue virus infection. The serum samples (n=17) were obtained in 2018 from patients attended by the public health system in Santarém municipality, located in the Amazon region of Brazil. Samples were submitted to ELISA (IgM) and also nested-PCR, presenting negative results to dengue virus in all tested samples. However, nested PCR detected five positive samples for B19V. The patients had fever, headache, and myalgia as the most frequent symptoms. To our knowledge, this is the first molecular detection of human parvovirus circulation in the west Pará region of Brazil, suggesting that the infection by this virus should be considered in all dengue-like cases, especially for risk groups like pregnant women.
