Exploring the Therapeutic Potential of Propolis: Insights into its Chemical Profile and Pharmacological Activities
International Journal of Development Research
Exploring the Therapeutic Potential of Propolis: Insights into its Chemical Profile and Pharmacological Activities
Received 17th November, 2024; Received in revised form 11th December, 2024; Accepted 22nd December, 2024; Published online 24th January, 2025
Copyright©2025, Karthik K V et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Propolis is a natural adhesive produced by honey bees. This study explored two extracts, methanolic and ethanolic, prepared through Soxhlet extraction and maceration, respectively. The antioxidative, antibacterial, and anticancer properties of these extracts were assessed. For quantification, flavonoid, phenolic, and tannin contents were determined in both extracts. The antioxidant properties of the extracts were evaluated using DPPH and ABTS radical scavenging assays. Antibacterial susceptibility test of the extracts was performed to evaluate their efficacy against gram-positive and gram-negative bacteria. Both extracts have also shown anti-cancer activity as well on leukemic cell line and hence can be taken into consideration for further pharmacological investigations along with their clinical applications.