Evaluation of the antioxidant activity of acetal and hexane extracts ofentada mannii (fabaceae) in vitro

This study aimed to evaluate the antioxidant activity of the acetal and hexane extracts of Entada mannii (Fabaceae) after conducting the polyphenolics assay. E. mannii is a plant used in the traditional treatment of diabetes in the south-east of Coast Ivory. The quantitative estimate of the polyphenol content of the acetal extract gave the following results: Total Phenolic Content (19.74 ± 2), total flavonoids (0.69 ± 0.03) and total flavanols (0.33 ± 0.02). As for the hexane extract, the respective contents obtained for these same compounds are: 9, 641 ± 1 ;0.39 ± 0.01 and0.3 ± 0.01. The evaluation of the antioxidant activity of the various extracts was carried out according to two methods: the free radical scavenging by the DPPH and the measurement of the reducing power (FRAP).The results obtained indicate that the acetal extract of E. manniicontains more polyphenolic compounds than the hexane extract. The acetal extract antioxidantproperties (AEEM, IC50 = 52.30 ±2.05) are also greater than those of the hexane extract (HEEM, IC50 = 70.51±1.84). This antioxidant activity could thus represent an additional asset for the use of this plant in the traditional treatment of diabetes and some pathologies related to oxidative stress.