Estimation of lipid profile in Preeclamptic and normal pregnant woman among Sudanese patients in Khartoum state

The objectives of this study are to assess the effect of pregnancy (in the third trimester) and pregnancy complicated by hypertension on lipid profile in Sudanese pregnant women. The study was carried out utilizing 120 women, including 40 non-pregnant women and unmarried (control), 40 pregnant women at the third trimester, and 40 women with preeclampsia. Their ages ranged from 17- 38 years. Serum was analyzed for total cholesterol, LDL cholesterol, HDL cholesterol, and triglyceride. The group of normal pregnant women showed significantly (P< 0.05) increased concentrations of, serum total cholesterol, LDL cholesterol, and triglyceride, compared to the non-pregnant women. And significantly (P< 0.05) decreased concentration of serum HDL cholesterol. The group of women with preeclampsia had significantly (P< 0.05) increased concentrations of, serum total cholesterol, LDL cholesterol, and triglyceride compared to the normal pregnant women. Beside that the women with preeclampsia showed a significant (P< 0.05) decrease in serum HDL cholesterol compared to normal pregnant women. When the women with preeclampsia were compared to the control, they showed significantly (P< 0.05) increased concentrations of, serum total cholesterol, LDL cholesterol, and triglyceride, and no significant changes in serum HDL cholesterol. We conclude that, dyslipidemia and are the features of pre-eclampsia in Sudanese pregnant women.