Effect of lead exposure on biochemical tests in blood of occupationally exposed workers in major sudanese cities
International Journal of Development Research
Effect of lead exposure on biochemical tests in blood of occupationally exposed workers in major sudanese cities
Received 24th February, 2017; Received in revised form 17th March, 2017; Accepted 14th April, 2017; Published online 18th May, 2017
Copyright©2017, Hythem S. A. Saeed et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
High lead level in blood is said to have adverse effects on human health. This study was conducted to determine blood lead, liver enzymes, triglycerides and total cholesterol levels in traffic policemen and petrol station workers. A total of 150 subjects were randomly selected from different cities of Sudan, in which 100 samples taken as exposed group and 50 as un-exposed (control). Blood lead concentration was determined by using atomic absorption spectrometer. Biochemical parameters were measured in serum using standard methods. Mean blood lead concentration in exposed group was found to be 32.2 µg /dl, whereas in control was 12.4 µg/dl. Result showed that serum aspartate transaminase (AST), gamma glutamyltransferase (GGT), alanine transaminase (ALT), total cholesterol (TC) and triglycerides (TG) were significantly higher in samples compared to control, while alkaline phosphatase (ALP) was significantly decreased in exposed group compared to control. Result indicated that long-term exposure to air lead pollution affects liver functions and deteriorates human health.
