Biochemical profile of individuals with HIV/AIDS in haart: A proposal for nutritional intervention using a bioactive food compound
International Journal of Development Research
Biochemical profile of individuals with HIV/AIDS in haart: A proposal for nutritional intervention using a bioactive food compound
Received 14th June, 2017; Received in revised form 18th July, 2017; Accepted 27th August, 2017; Published online 30th September, 2017
Copyright ©2017, Rosângela dos Santos Ferreira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
AIDS currently has chronic disease status because of the side effects of HAART. A study with 91 adult subjects undergoing HAART with or without hypolipidemic and/or hypoglycemic medication. Subjects were divided into groups A (GA) and B (GB) based on HAART and GB received 3.6 kg of Bioactive Food Compound (BFC) for three months. The variables were: immunological and virologic, biochemical parameters, HAART and BFC. Group A consisted of 2 NRTIs + 2 PIs (boosted with ritonavir) or 2 NTRIs + 1 NNRTI + 2 PIs, and this group was further divided into 2 subgroups: GA1 and GA2, consisting of atazanavir boosted with ritonavir and ritonavir boosted with lopinavir. Group B was formed by 2 NRTIs + 1 NNRTI. GB had a higher degree of immunodepression. The viral load was undetectable, and the exposure time to HAART was kept for more than two years. After 3 months of BFC consumption, GB presented better laboratory results for TG, TC, HDL-c, LDL-c and glucose levels. GA1 intra-group was a decrease in TG levels. In individuals without medication, it was possible to observe a decrease in TG levels, and a maintenance of the other parameters. The intra-group in GA2, using drugs to control lipids and glucose, it was decrease in TC and LDL-c in the same way as for individuals without medication, besides an increase in HDL-c. There is a need for multidisciplinary health interventions with people living with HIV / AIDS to control factors associated with chronic non-communicable diseases.