Synthesis and characterization of schiff's bases linked to new succinimides through phenyl ring moiety
International Journal of Development Research
Synthesis and characterization of schiff's bases linked to new succinimides through phenyl ring moiety
Received 05th April, 2017; Received in revised form 29th May, 2017; Accepted 26th June, 2017; Published online 31st July, 2017
Copyright ©2017, Ali Abdul Kareem Raheem. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Some Schiff bases linked to new Succinimides have been synthesized via multistep synthesis. The first step involved reaction of succinic anhydride with P-Amino Acetophenone producing N-(4-acetophenyl) succinamic acid which was subsequently dehydrated to the corresponding N-(4-aceto phenyl)succinimide via treatment with acetic anhydride and anhydrous sodium acetate; and this in turn when introduced in condensation reaction with various aromatic amines afforded the target new Succinimides Linked to Schiff's bases through phenyl ring moiety. Structures of the prepared compounds were elucidated on the basis of FTIR, 1HNMR and 13CNMR spectral data which agreed with the proposed structures. The newly synthesized compounds are expected to have biological activity since they are built from biologically active components including succinimide and Schiff base.