Status of adiponectin level in pcos and its relationship with body mass index (bmi) in kanpur region women with pcos
International Journal of Development Research
Status of adiponectin level in pcos and its relationship with body mass index (bmi) in kanpur region women with pcos
Received 19th June, 2019; Received in revised form 09th July, 2019; Accepted 17th August, 2019; Published online 28th September, 2019
Copyright © 2019, Dr. P. Satyanarayana et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Objective: Polycystic ovary syndrome (PCOS) is a common endocrine disorder associated with obesity. Earlier, studies showed a direct relationship between Adiponectin level and obesity, however, contrast results were, found in different studies. The present study investigated the status of Adiponectin level in PCOS and its relationship with body mass index (BMI) in Kanpur region women with PCOS. Methods: In this cross-sectional study, 80 women in the age group of 20-40 were enrolled, 40 women with PCOS were assigned as study group and 40 healthy women were selected as control groups. Fasting blood samples were then collected during the 2nd or 3rd day of menstruation for measurement of serum blood glucose (fasting blood sugar), and serum adiponectin levels. Anthropometric measurements were noted. Results: Mean BMI of the PCOS and control groups were 26.24±1.35 kg/m2 and 22.65±1.17 kg/m2, respectively (P <0.001). The mean total Adiponectin levels in study group was 11.69 ± 0.63 ng/mL and in the control group it was 14.38 ± 0.98 ng/mL (P = 0.0001). A significant relationship was found between Adiponectin level and BMI among women with PCOS (P < 0.05). Conclusion: Results of the present study indicated serum Adiponectin levels were significantly lower among women with PCOS and it is inversely associated with BMI and FBS.