Platelet-rich fibrin in maxillofacial surgery- review of literature
International Journal of Development Research
Platelet-rich fibrin in maxillofacial surgery- review of literature
Received 27th April, 2017; Received in revised form 09th May, 2017; Accepted 16th June, 2017; Published online 31st July, 2017
Copyright ©2017, Sujeesh Koshy et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
PRF technique was developed by Choukroun et al in 2001. Platelet Rich Fibrin (PRF) is autologous biomaterial which is the second-generation platelet concentrate. PRF has a favourable biological property that accelerate healing of soft tissue, and bone, giving a wide range of applications found in oral and maxillofacial surgery and other surgical fields. It is used to accelerate the healing of soft and hard tissue. In contrast to the PRP, the PRF is composed of autologous fibrin matrix in which a large amount of platelets and their growth factors are embedded. PRF-graft is used in augmentative techniques residual bone defects, alone or in combination with biomaterials. PRF accelerates the healing of soft tissue and reduces the possibility of dehiscence and exposure of the membrane.