Evaluation Of Inflammatory Infiltrate And Mesh Compression Present In The Leukocyte- And Platelet-Rich Fibrin (L-PRF) Network In Wistar Rats
International Journal of Development Research
Evaluation Of Inflammatory Infiltrate And Mesh Compression Present In The Leukocyte- And Platelet-Rich Fibrin (L-PRF) Network In Wistar Rats
Received 10th December, 2020 Received in revised form 24th December, 2020 Accepted 18th January, 2021 Published online 24th February, 2021
Copyright © 2021, Ivair Tavares Junior et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The purpose of study was to verify if the variation in the drainage time of the L-PRF clot promotes changes in fiber density and in the number of leukocy tes, from the drainage times of 1’, 2’, 3’ and 5’.An experimental model with Wistar rats, submitted to cardiac puncture to obtain blood was performed. After centrifugation, a PRF clot was obtained. The clots were drained for different times according to the group: 1’ (GII),2’ (GIII),3’ (GIV), 5’ (GV).The control group (GI) was composed of clots that did not undergo drainage, were removed from the tube and taken directly for fixation. Taking the clot as a whole, there is no statistically significant difference in the number of leukocytes between the groups, but the fibrin mesh density is higher in GIV samples compared to groups I, II and III, without any statistical difference to group V. Depending on the desired application in each case, clinicians should consider that the duration of drainage of blood clots will significantly affect thedensity andclot cell composition, even though there is only a difference of 1’between the compression times.
