Heat generation by gut flora metabolism and host cells bio-energy feedback

Cells, obtain energy from organic molecules, this energy is derived from the chemical bond energy in organic molecules to produce ATP and heat energy. In these growth independent reactions, energy sources were converted to heat energy. In the world, first time the energy of microorganism is absorbed, released or transformed one into another mechanism equation was discovered by Shagj J (Rolex awards Jambalyn Shagj: Heat generation and accumulation in the mammalian and human large intestine). Assumig the heat was spread over a 70 kg person and there was no heat loss, gut bacteria would raise body temperature by about 1.0 °C/h. The colonic epithelium drives 60%-70% of its energy from bacterial fermentation products such as acetate, propionate, butyrate, lactate, pyruvate. This phenomenon is called bio-energetics feedback of host cell and bacteria. The large intestine’s lenght of approximate family of a mammifier is demonstrated that the adaptation potential in the thermo-situation. It depends on there are evolvement, chronologic factor, geographic condition and abruptness of weather.