Studies on dna cleavage, antimicrobial screening and anticancer activity of zr(iv) and th(iv) metal complexes of dfmpm and glycine
International Journal of Development Research
Studies on dna cleavage, antimicrobial screening and anticancer activity of zr(iv) and th(iv) metal complexes of dfmpm and glycine
Received 24th March, 2017; Received in revised form 19th April, 2017; Accepted 07th May, 2017; Published online 16th June, 2017
Copyright© 2017, Gnana Glory Kanmoni et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The Zr(IV) and Th(IV) Schiff base complexs with di--formylmethoxybis(3-pentadecenylphenyl)methane (DFMPM) and glycine were synthesized and characterized by elemental analysis, conductivity measurements, electronic, IR, 1HNMR spectral measurements, Powder XRD and SEM. The conductance measurements indicate that all the complexes are non electrolytes. Infrared spectra indicate the coordination of imino nitrogen and carboxylato oxygen. The electronic 1HNMR spectral results indicate that both Zr(IV) and Th(IV) ions are octacoordinated and ligand is tetradentate. The Zr(IV) and Th(IV) complexes have better antimicrobial activity, DNA cleavage ability and anticancer activity.
