Cross sectional study to study clinical profile of blood culture positive typhoid fever patients

Introduction: Typhoid fever is highly prevalent in India with hight rate of morbidity and mortality. There is paucity of data from India on the clinical and investigational profile of proven typhoid fever patients. Thus this study has been taken up to study these aspects of typhoid fever. Aims and objectives: To study clinical profile of blood culture positive typhoid fever patients. Materials and Methods: Study was carried out in the Department of Pediatrics, Northern Railways Central Hospital, New Delhi. 100 patients with fever of more than 3 days duration were taken. Detailed history and examination of these patients were done and noted on a proforma .Investigations like Typhidot-M, Blood culture & S. Widal were done. Blood culture was done in second week of fever. Other tests for evaluation of other causes of fever were also done. Results: Clinical and investigative profile of typhoid fever patients had shown that distribution in male gender, hepatomegaly and raised ESR were associated with blood culture positive patients. Conclusion: .In our study we found that clinical profile of blood culture positive patients were found to have comparable symptoms and signs when compared to blood culture negative patients. Distribution of male patients, hepatomegaly and raised ESR were found to be significantly associated with blood culture positivity.