Neurological involvement by igg4-related disease: a case report

IgG4-related disease is a chronic fibroinflammatory condition characterized by swelling lesions, dense lymphoplasmacytic infiltrates, and abundant plasma cells containing IgG4 in affected tissues. The disease, although it can affect the central nervous system, does not have it as the main site of involvement. Thus, it is important to describe these cases to the scientific community. This article presents a case report of a 23-year-old female patient with IgG4-related disease, presenting with neurological involvement, with headache and eyelid ptosis, and several characteristic findings of the disease on imaging, histopathological and immunohistochemical analysis. The patient, still under follow-up, achieved partial improvement with the use of prednisone, requiring rescue therapy with corticosteroid-sparing agents.