Hyperbilirubinaemia in newborns: A Systematic review

Jaundice in newborns is characterized by the appearance of a yellowish tint to the skin and sclera of full-term as well as pre and post-term newborns and is often presente in the neonatal period affecting half to two thirds of newborns. It is characterized by elevated levels of indirect bilirubin or unconjugated bilirubin in serum concentration greater than 1.5 mg/dl. This study constitutes a bibliographic review on this condition, clinic, pathophysiology, risk factors, diagnosis and therapeutic approach. It was adopted as methodological procedure the bibliographic research, carried out through sources of books, articles and electronic documents indexed in the Virtual Health Library portal, in the databases MEDLINE and LILACS, and on the Scielo Brasil portal. The data collection showed that the neonatal jaundice is a pathology that requires a careful therapeutic approach due to its potential to reach the central nervous system.