Homeophatic effect of calcarea carbonica, calcarea phosphorica and calcarea fluorica in inorganic composition of dental pulp in rats

Introduction: Inorganic composition of pulp tissue is related to its regeneration potential in tooth mineralization processes. Objetive: The objective of the study was to evaluate the effect of administering Calcarea carbonica 6 CH, Calcarea phosphorica 6CH and Calcarea fluorica 6CH in inorganic composition of dental pulp. Methodology: Wistar rats (n=40) were divided in groups according to the experimented medication: GI-control group, GII – Calcarea carbonica 6CH, GIII- Calcarea phosporica 6CH, GIV – Calcarea fluorica 6CH and GV homeopathic formula composed by all of them. The animals received 3 drops of medication daily, corresponding to the group, during 21 days. The animals were sacrificed on the 22nd day and the incisor dental pulp was removed. Ca, P and K concentrations were determined by optical emission spectrometry (ICP-OES). The results were subjected to Analysis of Variance and Tukey´s Post Hoc Test (p≤0,05). Results: Groups GII and GV presented an increase in the concentration of Ca (80 and 88% respectively) and P (54 and 58% respectively) compared to the control group (GI) (p≤0,05). Groups GIII, GIV and GV presented an increase in concentration of K (17, 34 and 46% respectively) compared to the GI group (p≤0,05). Treatment with Calcarea carbonica, phosphorica and fluorica increased the animals’ body weight in comparison with the control group. (p≤0,05). Conclusion: Calcarea carbonica 6CH and the homeopathic formula composed of the three Calcareas increase the availability of calcium, phosphorus and potassium in pulp, which can contribute positively to dental mineralization processes. Calcareas phosphorica and fluorica 6CH, as well as their combination, increase the availability of potassium in the pulp tissue.