High-Functional Self-Lubricating Excipient Performance Comparison with Physical Blend

A microcrystalline cellulose-based excipient having improved lubrication sensitivity and flowability, whether utilized in oral solid dosage forms, in direct compression, wet and dry granulation tablet manufacturing, or hard capsule filling and dry syrup formulation. Self-lubricating excipient BARETab Lub is an agglomerate of microcrystalline cellulose particles and from 0.1 to 0.8 % lubricant Magnesium stearate, by weight of the Microcrystalline cellulose, wherein the microcrystalline cellulose and magnesium stearate particles are in intimate association with on each other. The lubricant magnesium stearate is used in pharma and Nutra as a novel lubricant to make solid oral dosage forms. Self-lubricating excipients don’t affect tablet properties like hardness, disintegration time, and dissolution of the tablet, BARETab Lub improves Particle BET surface area, and Physical properties. In this study, we will blend the self-lubricating excipient physical properties, BET surface area, FTIR, SEM, and the impact of blending time on the Self-lubricating excipient and physical mix of MCC and Magnesium stearate.