Effect of parity on plasma fibrinogen in normal pregnant Sudanese women

Background: The parity is the number of times that she has given birth to a fetus with a gestational age of (24) weeks or more, regardless of whether the child was born alive or was stillborn. The aim of this study is to shed more like on the role of effect parity on fibrinogen level.                                          
Objectives: study the effect of parity on the plasma fibrinogen in normal pregnant Sudanese women, and determination of levels of plasma fibrinogen in pregnant women Material and method: cross- sectional study was conducted at Algazeraand Khartoum states during October to November 2015. (120) normal pregnant women with age ranging (20 – 42) years, classified as (60) non pregnant women (nullparas) as control group, (30) multiparae and (30) grand multipara’s. 
Results: The concentration of fibrinogen in the multiparae mean (6.20) as compared to (8.52) mg/dl in the control group (P.value 0.266) was insignificant, Grand multipara mean (3.77) as compared to (8.52) mg/dl in the control group (P.value 0.015) were significantly decreased compared to control.
Conclusion: Normal pregnant multipara and grand multipara women fibrinogen levels are lower than in aged matched with non pregnant women. These changes are not directly associated with lipid metabolism during pregnancy (8).