Effect of heavy metal nickel on the lipid peroxidation and antioxidant parameters in the liver tissue of cirrhinus mrigala (ham.)

Metals are biologically important. If the threshold concentration of the metal increases in the environment, they may interfere with the metabolic activity of organisms. In the presenting study, an attempt was made to investigate the effect on nickel on oxidative stress and antioxidant enzymes in the liver tissue of Cirrhinus mrigala. The fish were exposed to sub lethal dose of 96 hr LC50 of nickel for 30days and removed the liver tissue as well as from control fish and studied the tissue lipid peroxidation (LPO), Reduced glutathione (GSH), glutathione peroxidase (GPx), Catalase (CAT), and superoxide dismutase (SOD). The present study of metal treated fish shows the increased level of lipid peroxidations and decreased level of reduced glutathione (GSH), glutathione peroxidase (GPx), catalase (CAT), superoxide dismutase (SOD) in the liver tissues of fish, Cirrhinus mrigala. These observed mean data were statically significant at P< 0.05 student ‘T’ test. The results are discussed with available literature