Clinical characteristics of multidrug-resistant escherichia coli at a tertiary care university hospital in Japan

Escherichia coli is the leading cause of various infectious diseases such as pneumonia, urinary tract and blood stream infections. Furthermore the emergenceof multidrug-resistant Escherichia coli has been focused worldwide. The objective of this study was to determine the clinical characteristics of multidrug-resistant Escherichia coli at a tertiary care university hospital in the central region of Japan. We determined the in vitro susceptibilities of 10 antimicrobial agents for 530 multidrug-resistant Escherichia coli in Japan. From antimicrobial susceptible results, these results indicated the over 60% of multidrug-resistant Escherichia coli had beta lactamase and fluoroquinolone resistant ability. Our results also revealed that the risk factors of multidrug-resistant Escherichiacoli were over 60 years, and department of urology. The emergence of multi-drug resistant Escherichia coli suggests that further aggressive surveillance is needed for providing useful information on the trends in antimicrobial resistance