Biochemical profile of individuals with HIV/AIDS in haart: A proposal for nutritional intervention using a bioactive food compound

AIDS currently has chronic disease status because of the side effects of HAART. A study with 91 adult subjects undergoing HAART with or without hypolipidemic and/or hypoglycemic medication. Subjects were divided into groups A (GA) and B (GB) based on HAART and GB received 3.6 kg of Bioactive Food Compound (BFC) for three months. The variables were: immunological and virologic, biochemical parameters, HAART and BFC. Group A consisted of 2 NRTIs + 2 PIs (boosted with ritonavir) or 2 NTRIs + 1 NNRTI + 2 PIs, and this group was further divided into 2 subgroups: GA1 and GA2, consisting of atazanavir boosted with ritonavir and ritonavir boosted with lopinavir. Group B was formed by 2 NRTIs + 1 NNRTI. GB had a higher degree of immunodepression. The viral load was undetectable, and the exposure time to HAART was kept for more than two years. After 3 months of BFC consumption, GB presented better laboratory results for TG, TC, HDL-c, LDL-c and glucose levels. GA1 intra-group was a decrease in TG levels. In individuals without medication, it was possible to observe a decrease in TG levels, and a maintenance of the other parameters. The intra-group in GA2, using drugs to control lipids and glucose, it was decrease in TC and LDL-c in the same way as for individuals without medication, besides an increase in HDL-c. There is a need for multidisciplinary health interventions with people living with HIV / AIDS to control factors associated with chronic non-communicable diseases.