Antibiotic susceptibility pattern of urinary tract infection causing pathogens isolated from diabetic patients

Urinary tract infection is one of the most commonly occurring infections among the patients with diabetes mellitus. The present study was focused on the antibiotic susceptibility of the UTI pathogens isolated from the diabetic patients. About 936 UTI organisms were isolated from 900 culture positive urine samples collected from the diabetic patients attending the government hospital. The incidence of UTI was recorded to 82% among the diabetic patients for the study period of two years from March, 2011 to February, 2013. Escherichia coli was found to be the major cause of UTI. About 10 different types of organisms isolated from the UTI samples were randomly chosen to test against the UTI antibiotics of dodecadisc rings of Hi-media with codes DE004 and DEO30 .The antibiotic susceptibility pattern revealed that Serratia marcescens was sensitive to 91% of antibiotics tested against and was resistant to 9% of antibiotics followed by Proteus mirabilis (87% and 13%), Staphylococcus aureus (70% and 17%), Citrobacter sp. (70% and 30%), Klebsiella sp. (70% and 30%), Methicillin resistant Staphylococcus aureus (61% and 17%), Enterobacter sp. (52% and 39%) and E. coli (48% and 39%). Among the antibiotics tested against the isolates; Netillin, Gatifloxacin and Levofloxacin revealed a 100% sensitivity followed by other antibiotics. About 50-60% of the isolates were multi drug resistant in which E. coli, Enterobacter sp., Klebsiella sp. and Citrobacter sp. revealed resistance to 30-39% of antibiotics such as, Cefacdroxil, Cefuroxime, Cotrimoxazole, Cefaclor and Nalidixic acid. E. coli was found to be the most resistant organism.