Analysis of the pulmonary tomographic pattern by the b.1.1.7 and p.1 variants of the sars-cov-2 virus

The SARS-CoV-2 virus has undergone several genetic mutations, which culminated in multiple waves of disease transmission. Computed tomography (CT) of the chest may be a diagnostic alternative complementary to RT-PCR to assess pulmonary involvement and assist in the therapeutic approach. To analyze the pulmonary tomographic patterns in the epidemic peaks of COVID-19 caused by the B.1.1.7 and P.1 variants of the SARS-CoV-2 virus. Cross-sectional, descriptive, analytical and retrospective study through the evaluation of 360chest CT scans of patients with COVID-19 in two epidemic peaks of the disease of April–September 2020(B.1.1.7) and October 2020–March 2021(P.1) in an area of the Brazilian Amazon. Were included patients >18 years old of both sexes. The pattern and degree of pulmonary involvement, distribution of lesions, affected segments and other CT findings were evaluated. Gender (p=0.289) and age group (p=0.314) did not vary significantly between periods. In the first, 70.6% had pulmonary involvement10-25% and in the second,43.3%. The presence of interlobular septa thickening was significantly observed in the first epidemic peak (81.9%) (p=0.002). Prevalence of women and age between 45-60 years. All had ground-glass lesions and the typical pattern of involvement prevailed in both analyses. The Alpha variant presented a higher degree of pulmonary involvement in relation to the Gamma variant.